Youthful

Fountain of Youth
I watched japanaese tameshitegatten health TV show that showed adiponectin fat cell hormone is correlated to long life. It says that being fat blocks circulation that fat cell need to produce adiponection and stomach exercise helps.
11-19-2015
I came up with unified theory of why some lots of things extend life.
Basically circulation to fat, circulating rest, or catalyst for adiponection to extend life.  Perhaps slows biological clock in genes.
There’s also possibility that adiponection is just correlate to same thing that help longer youth and does not promote it. For example,high adiponection means fat cell can collecting fat from blood for better whole body circulation.  It make sense that good body circulation promote long life.

1) Buckyball(carbon sphere) and extra virgin olive oil help lube so more circulation or being catalyst.
2) Exercise, slightly starvation,not fat help circulation to fat
3) Beef fat have higher melting point(big animal have easier time generating heat), so it is harder for human to burn.
4) Sugar promote bad stomach microbe such as candida(which make fat?) and craving. Carb ristrict diet might help reduce candida etc.
5) Diabetes correlate to opposite of things promote adiponection
6) Sex is good exercise
7) Pregnancy promote various hormones.  Afterward,stomach is loose(better circulation?) It also melt the fat for milk. It also gives mother stem cells from baby.
8) Growth hormone can help being youthful.  It might be helped by same things that promote higher adiponection. Or Perhaps adiponection promote growth hormone.
9) Variation in life.  Genetically humans develop in seasonal and other variations.  This is also like wanting vacation.  This and other variation might help rebalanced excessive routine/repetition/concentration of things from doing same routine(like eating same food and developing same muscles only). Things like light use of alcohol/marijuana/mushroom probably provide variation break from routine and help develop different area.
10) Testosterone might hasten growth at expense of hasting biological clock

One thought on “Youthful

  1. real7777 December 4, 2015 / 8:49 pm

    Personal choice and actions on life extension and genetic engineering for cognitive, performance enhancement of life extension
    antiaging, cognitive enhancement, genetic engineering, life extension, longevity, performance enhancement, transhuman, transhumanist

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    Gene editing costs are dropping below $1000.

    George Church, a researcher at Harvard University and a proponents of CRISPR, says that, considering the lack of clear regulatory frameworks for genetic engineering use, we must expect those interested in genetic augmentation to use the tool.

    Church noted in a speech Tuesday that athletes and others interested in body augmentation have already taken advantage of just about every technology we’ve developed. Those in the transhumanist movement (many of whom are seeking immortality, or at the very least a long extension of natural human lifespans) see CRISPR as a potential tool they could use to augment themselves.

    Currently it appears that their are a lot of side effect negative epigenomic changes being passed down via lifestyle of parents. Obesity and smoking cause epigenomic changes.

    Controlled enhancement

    Those interested in enhancement are gung-ho about experimenting on themselves. There are athletes who take stem cell injections to get over injury faster; Silicon Valley types who use nootropics and other “smart drugs” not approved by the Food and Drug Administration to potentially increase their brain function; and people who try things like transcranial direct current stimulation, which uses low electrical currents applied to the head to stimulate neuron function.

    About ten million people worldwide use steroids. Most of them are not competing in pro sports and do it for appearance or just the desire for greater strength and performace. There are millions that inject poison (Botox) into their face to smooth wrinkles.

    When it comes to people using CRISPR to augment themselves or their children, “some people say ‘I can’t imagine it happening’ And George Church says, ‘You have to imagine it happening.’”

    Church and some others who work with CRISPR believe that it’s already safe enough for additional research in humans, but, in the only known test of the technology on human embryos, CRISPR was largely ineffective in editing the desired genes. A breakthrough announced earlier this week enhances CRISPR’s accuracy and may be key to future human studies. As those eventual studies are conducted and as the technology becomes more consistent, Church believes somatic gene therapies, which target adult body cells (and could in theory be used by adults to alter themselves) will inevitably come next.

    “Enhancement will creep in the door,” Church said. “The point is that [human enhancements] will come after very serious diseases and they will be spread by somatic gene therapies.”

    Metformin is an antidiabetic drug which might have life extension properties and is now available without prescription in the Canary Islands

    Kern Pharma’s in the Canary Islands is apparently offering Metformin without prescription. There are doctors and researchers who have chosen to personally get into Metformin and other antiaging medications.

    The most common adverse effect of metformin is gastrointestinal irritation, including diarrhea, cramps, nausea, vomiting, and increased flatulence; metformin is more commonly associated with gastrointestinal side effects than most other antidiabetic drugs. The most serious potential side effect of metformin use is lactic acidosis; this complication is very rare, and the vast majority of these cases seem to be related to comorbid conditions, such as impaired liver or kidney function, rather than to the metformin itself.

    Metformin has also been reported to decrease the blood levels of thyroid-stimulating hormone in people with hypothyroidism, The clinical significance of this is still unknown.

    Millions are ordering Viagra and Cialis from overseas Pharmacies for enhanced sexual performance or overcome erectile dysfunction.

    Researchers will begin testing Metformin, a medication used to treat diabetes, as an anti-aging drug in a clinical trial next year.

    When it’s used for treatment for type 2 diabetes, the drug reduces the amount of glucose produced in the liver, but researchers believe that it may also have the ability to slow down the aging process in individual cells by increasing oxygen released into each cell.

    Reducing the biological effects of aging would mean the possibility of increasing lifespans, staving off aging-related diseases like Parkinson’s and Alzheimer’s and perhaps allowing humans to live into their 110s or 120s, the research suggests.

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